It seems with the latest 3dxWare driver some devices loose application specific settings and the ability to have macros and radial menus that are application specific. That is not cool at all.
The keyboard settings has a tagoole to turn-off global settings and turn on application specific settings. The Number Pad and CAD Mouse Pro Wireless doesn't seem to have a toggle to turn off global buttons and radial menus. This is such a mess. It's so annoying.